To assess whether these reflects the same signal, we performed colocalization analysis in the region ±200 kB around rs53412514 using Coloc package in R17 with coronary atherosclerosis results from FinnGen and pulse pressure GWAS results from Evangelou et al.16 The probability for shared signal (PP4) was 97.1%, further validating MFGE8 locus is associated with pulse pressure (Supplementary Fig. 10). The gene discussed is MFGE8; the disease is coronary atherosclerosis.