The one variant (rs118042209) in the credible set of TMEM200A locus was associated with multiple disease endpoints representing major coronary heart disease (CHD) in FinnGen, including coronary atherosclerosis, ischemic heart disease and angina pectoris, whereas the lead variant in the PRG3 locus was associated with cardiomyopathy. The gene discussed is TMEM200A; the disease is coronary artery disorder.