TP53 and cancer: In addition, the distribution of aberrations of RET and top-ten co-occurring genes, such as TP53 (n = 162; P < 0.001), PIK3CA (n = 84; P < 0.001), PTEN (n = 79; P < 0.001), and CDKN2A (n = 76; P < 0.001), were further analyzed across 32 types of TCGA cancers using OncoPrint (Fig. 7B).