First, we found that high RET levels were positively associated with poor patient OS in nine cancer types including cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), esophageal squamous cell carcinoma (ESCA), HNSC, KIRC, KIRP, LICH, SARC, STAD and UCEC. Here, RET is linked to esophageal squamous cell carcinoma.