Similarly, as shown in Table 2, tumor depth (HR = 2.615, 95% CI: 1.624–4.210, P < 0.001), lymph node metastasis (HR = 1.900, 95% CI: 1.313–2.749, P = 0.001) and STING methylation (HR = 2.619, 95% CI: 1.742–3.938, P < 0.001) could also serve as the independent prognostic factors for DFS of LUAD patients among the variables examined. Here, STING1 is linked to metastatic malignant neoplasm in the lymph nodes.