As shown in Supplementary Table S8, after univariate analysis, 4 factors, including tumor depth (HR = 2.297, 95% CI: 1.559–3.385, P < 0.001), lymph node metastasis (HR = 2.657, 95% CI: 1.969–3.587, P < 0.001), tumor stage (HR = 2.628, 95% CI: 1.919–3.597, P < 0.001), and STING expression (HR = 0.562, 95% CI: 0.362–0.873, P = 0.010), were identified as risk factors for OS of LUAD patients. This evidence concerns the gene STING1 and metastatic malignant neoplasm in the lymph nodes.