We confirmed downregulation of IL6 signaling, as well as the downregulation of IL6, NFKBIZ, and GADD45B in a large-scale transcriptomic study of IPF versus healthy lung tissue (Yang et al., 2013) as well as showing decreased expression of IκBζ in alveolar epithelial cells in IPF lung tissue. The gene discussed is GADD45B; the disease is idiopathic pulmonary fibrosis.