NFKBIZ and idiopathic pulmonary fibrosis: We confirmed downregulation of IL6 signaling, as well as the downregulation of IL6, NFKBIZ, and GADD45B in a large-scale transcriptomic study of IPF versus healthy lung tissue (Yang et al., 2013) as well as showing decreased expression of IκBζ in alveolar epithelial cells in IPF lung tissue.