TGFB1 and idiopathic pulmonary fibrosis: Downregulation of interferon-associated gene expression has previously been reported in cells isolated from the peripheral blood of patients with IPF (Huang et al., 2021), and we identified a suppression of type I interferon innate immune responses in IPF lung tissue, confirming through in vitro studies that TGFβ was sufficient to suppress type I IFN-regulated gene expression.