Comparison of spatially related IPF ROIs (IPF adjacent alveolar septae, immune infiltrate, and fibroblastic foci) showed enrichment of cell processes involving EMT, ECM, and motility in fibroblastic foci and adjacent alveolar septae (Figure 2J), with signaling pathways including PDGF and TGFβ superfamily signaling enriched in fibroblast foci (Figure 2H). This evidence concerns the gene TGFB1 and idiopathic pulmonary fibrosis.