scRNA-seq using the 10x Genomics Chromium droplet-based methodology was performed in tandem with cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq; see STAR Methods) on CD45+ immune cells isolated from lesional skin biopsies of 8 patients with psoriasis, comparable in cohort size to recent scRNA-seq studies (Tables S1 and S2).4 Here, PTPRC is linked to psoriasis.