KIF11 and xeroderma pigmentosum group D: The overexpression of either Eg5/S1033A, Eg5/S1033E, or Eg5/WT was unable to rescue the RARβ2 expression deficiency observed in XPD/R683W cells (Fig. 8H), which was in accordance with the fact that Eg5 neither targeted nor influenced the formation of the transcription preinitiation complex (PIC; fig.