No differences were observed between XPD/R683W and XPD/WT cells for the accumulation of Eg5 or several established mitotic markers such as Polo-like kinase 1 (which triggers G2-M transition and establishes bipolar spindle) (31), AURORA B (which controls condensation of the chromosomes and their attachment to the mitotic spindle) (32), and H3-pS10 (the mitotic marker phospho–histone H3 serine-10). This evidence concerns the gene PLK1 and xeroderma pigmentosum group D.