To assess whether TB disease severity classified into three classes (SCI, SCII, and SCIII) had an association with the production of IFN-gamma, TNF-alpha, IL-6, IL-17A, IL-10, and IL-4, we analyzed the level of each cytokine in both helminth infected and helminth negative TB patients based on their severity classes, separately. This evidence concerns the gene IL6 and tuberculosis.