Thus, to discriminate the two tauopathies, we hereby propose JUN(B,D)HIGH, FOS(L1,L2)HIGH as well as the involvement of DUX4, KLF5, MAX::MYC, PAX6, and PPARG to support the identity of CBD-originated astrocytes (Fig. 6c–e). This evidence concerns the gene PAX6 and tauopathy.