We observed a significantly higher rate of pTau-positive astrocytes (TAs and APs) with MAP3K8 expression compared to GFAP positives in both tauopathies (PSP: 0.83 vs. 0.42, ncells = (118; 23), ncases = 4; CBD: 0.79 vs. 0.37, n = (83; 34), ncases = 4) (Fig. 7a). This evidence concerns the gene MAP3K8 and supranuclear palsy, progressive, 1.