Kai Yin et al. took the lead by analyzing the role of miRNA‐433 in glioma and concluded that miRNA‐433 could be inhibited by CircMMP1, thereby attenuating the inhibitory effect of miNRA‐433 on the downstream target gene High mobility group box 3(HMGB3) and finally promoting glioma progression.56 The gene discussed is HMGB3; the disease is central nervous system cancer.