By contrast, mild COVID‐19 associates with effective type I IFN responses, including expression of type I IFNs themselves and IFN‐stimulated genes, which are probably essential to clear the virus infection and orchestrate adaptive immunity accordingly (Arunachalam et al, 2020; Schulte‐Schrepping et al, 2020; Stephenson et al, 2021). The gene discussed is IFNA1; the disease is viral infectious disease.