In vivo, a multitude of cytokines, including IL‐1β, IL‐1RA, IL‐7, IL‐8, IL‐9, IL‐10, CXCL10, IFN‐γ, and TNF‐α are upregulated in the plasma of COVID‐19 patients, especially in cases with the severe outcome (Huang et al, 2020). The gene discussed is IFNG; the disease is COVID-19.