According to Yan and colleagues, non-survivors with diabetes had higher levels of leukocyte count, neutrophil count, C-reactive protein, pro-calcitonin, ferritin, receptors of interleukin-2, interleukin-6, TNF-α, and lower lymphocytic count than survivors, which indicated diabetic non-survivors had more sever inflammatory response [21]. This evidence concerns the gene CRP and diabetes mellitus.