Interestingly, hyponatremia was reported as one of the most common electrolyte abnormalities during the SARS pandemic in 2003.19 Nearly 60% of patients reported low sodium levels in a study from Hong Kong.19 Similarly, hyponatremia is one of the most common electrolyte abnormalities in patients with SARS-CoV-2 infection.4,5 The pathogenesis of hyponatremia in patients with COVID-19 infection is uncertain; however, low serum sodium during a COVID-19 infection seems to be primarily due to an inappropriate increase in ADH secretion. This evidence concerns the gene AVP and Hyponatremia.