Thus, all CFTR pathologically relevant variants previously known as “cystic fibrosis-causing, severe”, “cystic fibrosis-causing, mild” and “non-cystic fibrosis-causing” [34] will be classified as “predisposing” in the context of CP, with the conventional cystic fibrosis-based categories being provided in parentheses. This evidence concerns the gene CFTR and cystic fibrosis.