It was also reported that netrin-1 was upregulated in multiple malignancies including glioma [32], breast cancer [26], ovarian malignancies [33], non-small cell lung cancer [34], hepatocellular carcinoma [35], melanoma [36] and medulloblastoma [27] which was consistent with our results. The gene discussed is NTN1; the disease is non-small cell lung carcinoma.