Furthermore, the CCK-8 assay, colony formation assay, nude mouse xenograft assay (the tumor image is indicated in Fig. 6K) and Transwell assay showed that the change in cell proliferation ability and invasion capability after knockdown of YTHDC1 was diminished after coknockdown of ANXA1 in 786-O and A498 cells (Fig. 5F-K). The gene discussed is ANXA1; the disease is neoplasm.