However, the expression of genes described as markers of late AD stages [47] was unaffected: TREM2 (triggering receptor expressed on myeloid cells 2; p = 0.197), LPL (lipoprotein lipase; p = 0.485) and CST7 (cystatin F; p = 0.240) (Additional file 4: Fig. S4). This evidence concerns the gene TREM2 and Alzheimer disease.