Jeon K et al. tested 46 cancer cell lines using targeted bisulfite PCR sequencing involving the five cancer types of colon, biliary tract, liver, lung, and stomach and found that a CpG site (chr5: 38557143) in LIFR, which was located within two selected CpG sites of cg18174928 (chr5: 38557085) and cg12602374 (chr5: 38557162) in our studies, was heavily methylated in colon cancer cells only but not in other cancer cell lines [38]. Here, LIFR is linked to cancer.