Previous reports have indicated that AML with t(9,11) is associated with a better prognosis than other 11q23 abnormalities [6], and the expression of ecotropic viral integration site 1(EVI1) or fms-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutation was a poor prognostic factor [23, 43]. Here, MECOM is linked to acute myeloid leukemia.