The KEGG pathway analysis demonstrated that DEGs were mainly enriched in several pathways associated with invasiveness and metastasis of cancer, such as PI3K − Akt signaling pathway, Wnt signaling pathway, Hippo signaling pathway, Focal adhesion, ECM − receptor interaction, and Regulation of actin cytoskeleton (Fig. 4E and F). The gene discussed is AKT1; the disease is cancer.