Focusing on immature T-ALL (=33), RNA microarray revealed that 64 DEG (44 down- and 20 up- regulated) distinguished cth+ (=11) from cth− (=22) cases: MYCN (up-regulated; fold change 5.57) (Fig. 2a) and RGCC (down-regulated; fold change of −8.02) were amongst the top deregulated genes (Supplementary Table 13 and, Fig. 2b). This evidence concerns the gene CTH and acute lymphoblastic leukemia.