Among cases with a chromotriptic chromosome 7, case no. 10 had a 2.9 Mb deletion, at 7p12.3-p12.1, involving IKZF1, which was also deleted in 4 cth− T-ALL, whereas case no. 3, had a deletion of EZH2, at 7q36. This evidence concerns the gene EZH2 and acute lymphoblastic leukemia.