Moreover, the IL-5-anchored CCAR-T cells maintained effective control of asthma-related conditions for up to three months (Fig. 5g–l; Supplementary Fig. S9), including the eosinophil levels in BALF (Fig. 5h, i), peripheral blood (Supplementary Fig. S9a) and bone marrow (Supplementary Fig. S9b), IL-5 levels in BALF (Fig. 5j) as well as the inflammatory infiltration in the airway (Fig. 5k, l). Here, IL5 is linked to asthma.