SDC1 and Miyoshi myopathy: We next showed that % CD138+ cell lysis induced by PL33 vs. ER79 was augmented as early as 4 h with co-treatments with 2 nM LY-411575 or 1 μ DAPT in co-cultures of 2 target MM cell lines with PBMCs (E:T = 6:1) or T cells (E:T = 3:1) from MM patients (n = 3) (Supplementary Fig. S2A).