To summarize, TDO2+ myofibroblasts were mainly located distally from tumor nests, and these cells attracted CD4+ T cells and CD8+ T cells through the CXCL9/CXCL10/CXCL11/CXCR3 axis, which may have prevented T cells from accessing tumor nests. This evidence concerns the gene CXCL9 and neoplasm.