CD274 and cancer: When evaluating survival analysis, we found that PD-1 (HR 2.59; p = 0.04), PD-L1 (HR 6.46; p < 0.01) and cAMP+ (HR 3.04; p = 0.02) expression were independent predictors of cancer-specific mortality (receiver operating curve [ROC]: 0.77) (Table 3).