ACE and atherosclerosis: The top networks included “ACE-RAGE signaling pathway in diabetic complications,” “fluid shear stress and atherosclerosis,” “HIF-1 signaling pathway,” “TNF signaling pathway,” “VEGF-VEGFR2 signaling pathway,” and “Insulin resistance–Homo sapiens.” In this network, the NFKB1 gene encoding for Nuclear Factor Kappa B Subunit 1 showed the highest degree value.