MAP2K7 and age-related macular degeneration: Last, of note, investigational compounds such as MAP kinase inhibitor (SB203580) and MEK inhibitor (U0126) also strongly correlate with the AMD-risk genes although this class of drugs is poorly understood to date but may exhibit antineoplastic activities along with notable toxicities (Tables 3, 4, 5, 6, 7, 8–9).45