Human KCTD7 patients display pronounced motor defects that can manifest as ataxia, tremors and dyskinesia (Dai et al., 2019; Farhan et al., 2014; Kousi et al., 2012; Kozina et al., 2020; Mastrangelo et al., 2019; Blumkin et al., 2012; Staropoli et al., 2012). Here, KCTD7 is linked to Ataxia.