IL10 and infection: Several factors may contribute to this picture in affected patients, such as infection of SARS-CoV-2 in T-lymphocytes through the ACE2 receptor [23], involvement of secondary lymphoid organs such as spleen and lymph node [24], and also the COVID-19-characteristic cytokine storm, where elevated levels of TNF-symbol, IL-6, and IL-10 are associated with lymphocyte depletion [25].