Consistent with the above findings from the in vivo efficacy study, histopathological analysis using hematoxylin and eosin (H&E) staining and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) revealed a massive amount of apoptotic tumor cells in tissues from Au‐AR DBD PROTAC‐treated mice and enzalutamide‐treated mice (Figure5G). The gene discussed is AR; the disease is neoplasm.