Exceptions include ACE2, TMPRSS2, TMPRSS4 genes in ESCA samples; TMPRSS2 gene in STAD and PAAD samples; CTSL and NRP1 genes in COAD and READ samples; and FURIN gene in COAD, READ, STAD and PAAD samples. This evidence concerns the gene TMPRSS2 and pancreatic adenocarcinoma.