Although the GWAS summary statistics from the COVID-19 HGI represent multiple ancestries and the signal at the ELF5 locus has recently been replicated in a Brazilian cohort83, the pQTL instruments are based on a single ancestry and genetic studies of plasma abundances of proteins in other ancestries may reveal additional candidate proteins, that may help to explain the variable prevalence of adverse COVID-19 outcomes across ethnicities8. The gene discussed is ELF5; the disease is COVID-19.