Notably, M2-like tumour-associated macrophages (TAMs), including CD206- and PD-L1-positive macrophages and microglia, infiltrated the tumour mass in each group at marked frequencies in the tumour mass (day 28), regardless of EZH2-92aa KD or the administration of NK cell therapy (Supplementary Fig. 7e). The gene discussed is CD274; the disease is neoplasm.