IGHE and parasitic infectious disease: To do this, we first constructed correlation matrices to identify significant positive and negative relationships between targets (parasitemia, gametocytemia, numbers of parasite oocysts in infected mosquitoes, and blood 16S copy numbers) and sources (ileal MC numbers, levels of plasma and ileal cytokines and chemokines, plasma IgE, plasma Mcpt1, Mcpt4, and histamine) for depleted and baso (+) mice over time following infection (Supplemental Fig. 3).