To examine the role of KDM1A in HCC cell growth, we knocked down KDM1A in HLF human liver cancer cells and detected significant decrease in cell proliferation (Figs. 1A and S1D), which could be ameliorated by expressing exogenous KDM1A (Figs. 1B and S1E). This evidence concerns the gene KDM1A and hepatocellular carcinoma.