LAMP1 and infection: Ectopic expression of LAMP1-WT or LAMP1-d384 resulted in a modest, ~3-fold, increase in virus fusion and single-cycle infection of both A549 and DF-1 cells, although hLAMP1 expression somewhat more strongly enhanced infection of DF-1 cells compared to A549 cells (Fig 2B and 2D, for raw data, see S2A and S2C Fig).