Kaplan-Meier analysis indicated that decreased SPIB expression correlated with a poor prognosis in CESC, LUAD, HNSC, SKCM, SKCM-M, READ, and OV, whereas increased SPIB expression was associated with poor prognosis in GBMLGG, LGG, KIRP, KIPAN, GBM, KIRC, THYM, and UVM (Figure 4B, 4C). Here, SPIB is linked to cervical squamous cell carcinoma.