Strikingly, exogenous HGF administration significantly ameliorated the Men1 deficiency‐induced degree of kidney injury and the severity of renal fibrosis in the mice that underwent UUO compared with that in the vehicle group, as determined by H&E, IHC and Western blot analysis (Figures 7E–H and S7G–J). The gene discussed is HGF; the disease is renal fibrosis.