NKX3-1 and Familial prostate cancer: These results were further confirmed in the Chinese Prostate Cancer Genome and Epigenome Atlas (CPGEA) prostate normal and tumor samples (N = 134).[14] As shown in Figure 2, the risk alleles of the significant SNPs were significantly associated with lower expression of NKX3‐1 in both normal and tumor tissues of prostate in the Chinese population.