An analysis of the clinicopathological characteristics of HCC patients in the group with high FOXA1 expression group and the group with low FOXA1 expression revealed that the group with high FOXA1 expression had a lower proportion of male patients, a lower age of onset, and higher AFP expression than the group with low FOXA1 expression, but no significant differences in the race, cancer stage, or vascular invasion were found between the two groups (P > 0.05, Table 1). The gene discussed is AFP; the disease is cancer.