DISC1 and schizophrenia: Previous studies also showed that both patients with schizophrenia and their unaffected siblings shared similar alterations in the ITG (Liu H. et al., 2012; Zhu et al., 2018), and the neural activity of ITG was regulated by regulating by the Disrupted-in-Schizophrenia-1 gene (Gou et al., 2018), suggesting that the ITG might be a potential biomarker of endophenotype for schizophrenia.