The trend in anterior pituitary hormone levels was inconsistent in the stroke patient population compared to the healthy control population, with GH levels increasing significantly after onset [IQR 0.356 (0.161, 0.738) μg/L vs. 0.137 (0.057, 0.411) μg/L] and remaining high for 5 days, TSH levels decreasing significantly [IQR 0.7833 (0.4215, 1.2340) mIU/L vs. 1.9290 (1.2080, 2.8040) mIU/L] and then increasing gradually, and FSH, LH and PRL levels showing no significant change (Supplementary Figure S2). Here, GH1 is linked to stroke disorder.