This study also yielded consistent results, finding that among the indicators tested, E, NE, 24-h UFC, and GH had the best correlation with MRI or CT brain tissue damage volume assessment at stroke onset for prognosis and disease severity, with E correlating most strongly with lesion volume (r = 0.468 P = 0.000), NE (r = 0.403 P = 0.003), F (r = 0.270 P = 0.035), 24-h UFC (r = 0.364 P = 0.014), and GH (r = 0.357 P = 0.011). Here, GH1 is linked to stroke disorder.