VDR and chronic kidney disease: Vitamin D forms 25-OH-D3 through the action of 25-hydroxylase and generates the active form of 1,25-hydroxyvitamin D3, exerting biological effects, and the kidney is the basic target organ of vitamin D. In addition, the analysis of related influencing factors found that the age of CKD patients, DM, and vitamin D receptor agonist had a certain correlation with RTI.