LRRK2 and Parkinson disease: A statistical meta-analysis of human gene expression in response to M. tuberculosis infection identified several enriched pathways, such as the LRRK2 pathway in PD (Wang et al., 2018), which play a critical role in regulating the central nervous system (CNS) immune milieu in PD patient (Cookson, 2017; Kim and Alcalay, 2017).