There was no significant difference in albumin between HEN and NOD groups (WMD = 0.05, 95% CI: -0.03 to 0.13, <i>P</i> = 0.20).<h4>Conclusion</h4>HEN improved nutritional status and quality of life (QOL) in postoperative patients with EC and reduced fatigue and the incidence of postoperative pneumonia. This evidence concerns the gene ALB and dentatorubral-pallidoluysian atrophy.