Lastly, previous studies showed that neonatal C57BL/6J mice succumb to infection when challenged with the parental VSV virus or with VSV virus where the glycoprotein (G) was replaced by the Ebola Zaire glycoprotein, however C57BL/6J mice do not succumb when challenged with VSV virus where G was replaced by the Ebola Reston glycoprotein or with SARS-CoV-2 spike protein (18). This evidence concerns the gene ART4 and infection.