Among the 21 lncRNAs, 14 lncRNAs (HOTAIRM1, LINC01082, LINC00460, USP30-AS1, AC096531.2, CASC15, CT75, LINC00574, LINC01711, LINC02593, MIR181A2HG, SLC25A21-AS1, WEE2-AS1, and ZEB1-AS1) were significantly differentially expressed between CRC and adjacent normal tissues. The gene discussed is WEE2; the disease is colorectal carcinoma.