Figure 1B shows the prognostic values of the 11 m6A-related metabolic pathways in the STS patients. A total of 8 m6A regulators (VIRMA, METTL3, LRPPRC, ELAVL1, YTHDC1, ALKBH5, YTHDF2, METTL14) associated with 11 metabolic pathways that play a key role in the prognosis of STS were screened, and their co-expression networks were showed in Figure 1C. These 11 m6A-related metabolic pathways were ranked using the RSF algorithm. Pyrimidine metabolism, fructose and mannose metabolism, and linoleic acid metabolism were the top 3 m6A-related metabolic pathways (Figure 1D). The gene discussed is VIRMA; the disease is telomere syndrome.