MALT1 overexpression increased p-IκBα (P<0.01) and p-p65 expressions (P<0.01) (Figures 6A, B), also elevated p-JNK (P<0.05) and p-c-Jun expressions (P<0.05) (Figures 6A, C), but less affected p-mTOR or p-p70S6K expressions (Figures 6A, D) in RA CD4+ T cells. This evidence concerns the gene CD4 and rheumatoid arthritis.