TIMP1 and systemic sclerosis: We observed higher production of angiogenin (p=0.004 and p=0.008), angiopoietin 1 (p=0.03 and p=0.02), PDGF-AA (p=0.09 and p=0.04) and TIMP-1 (p=0.03 and p=0.05) in B cell culture supernatants from SSc patients compared to HC, both with and without stimulation (respectively).