CXCL8 and obstructive sleep apnea syndrome: However, we still did not obtain any causal effects of OSA on IL-6 [estimate: 0.067, 95% CI = (−0.071, 0.205), p = 0.341], IL-8 [estimate: −0.069, 95% CI = (−0.200, 0.061), p = 0.297] and IL-18 [estimate: −0.043, 95% CI = (−0.163, 0.078), p = 0.488] by IVW (Supplemental Table 6 and Supplemental Figure 8A)