RHBDF2 and gastric cancer: Other CAF-related genes, such as mucin 1 (MUC1), Krüppel-like Zinc-Finger Transcription Factor 5 (KLF5), tumor endothelial marker 1 (TEM1), vascular adhesion molecule 1 (VCAM1), periostin (POSTN), lysyl oxidase like 2 (LOXL2), neuropilin-2 (NRP2), rhomboid 5 homolog 2 (RHBDF2), and serum amyloid A1 (SAA1), are characterized by high expression of genes associated with a poor prognosis in patients with GC (12, 16–22).